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Deadliest/large-loss fires
| Rank | Event | Date | Number of deaths |
| 1 | The World Trade Center New York, NY |
September 11, 2001 | 2,666 |
| 2 | Iroquois Theater |
December 30, 1903 | 602 |
| 3 | Cocoanut Grove night club (PDF, 2.5 MB) |
November 28, 1942 | 492 |
| 4 | Ohio State Penitentiary Columbus, OH |
April 21, 1930 | 320 |
| 5 | Consolidated School gas explosion (PDF, 826 KB) New London, TX |
March 18, 1937 | 294 |
| 6 | Conway's Theater Brooklyn, NY |
December 5, 1876 | 285 |
| 7 | Rhythm Club Natchez, MS |
April 23, 1940 | 207 |
| 8 | Lakeview Grammar School (PDF, 585 KB) Collinwood, OH |
March 4, 1908 | 175 |
| 9 | Rhodes Opera House Boyertown, PA |
January 12, 1908 | 170 |
| 10a | Ringling Brothers Barnum & Bailey Circus Hartford, CT All visitors: Read a free overview (PDF, 623 KB) from NFPA's The Quarterly, July 1944. |
July 6, 1944 | 168 |
| 10b | Alfred P. Murrah Federal Building |
April 19, 1995 | 168 |
| 12 | Beverly Hills Supper Club Southgate, KY Members: read NFPA's fire investigation report on this incident (PDF, 7.3 MB). |
May 28, 1977 | 165 |
| 13 | Triangle Shirtwaist Company (PDF, 860 KB) New York, NY |
March 25, 1911 | 146 |
| 14 | Eddystone Ammunition Company plant explosion Eddystone, PA |
April 10, 1917 | 133 |
| 15 | Cleveland Clinic Hospital (PDF, 351 KB) Cleveland, OH |
May 15, 1929 | 125 |
| 16 | Winecoff Hotel (PDF, 1.6 MB) Atlanta, GA |
December 7, 1946 | 119 |
| 17 | The Station Nightclub |
February 20, 2003 | 100 |
| 18 | Our Lady of the Angels School |
December 1, 1958 | 95 |
| 19 | Happy Land Social Club New York, NY Members: read NFPA's alert bulletin on this incident (PDF, 247 KB). |
March 25, 1990 | 87 |
| 20 | MGM Grand Hotel NFPA members: Read NFPA's fire investigation report for free. (PDF, 7 MB) |
November 21, 1980 | 85 |
Source: NFPA archive files, 1984 Fire Alamanac, and The Great International Disaster Book by James Cornell, Pocket Books New York, 1976.
Disclaimer: Death tolls are based on information in NFPA’s records. Please contact us at osds@nfpa.org to provide any updated information.
Updated: 3/08